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Web the drug trodusquemine was given to mice on a high fat diet in 2017 and was shown to melt away the fat inside. Web this article reviews the evidence on the physicochemical, cellular, animal model and clinical levels of how squalamine and. Web following a landmark 2017 research paper from the aberdeen cardiovascular and diabetes center, which showed that the. Web a drug that blocks the effects of an enzyme called ptp1b, which is involved in the development of aortic.